Klox Technologies proprietary technology platform utilizes FLE to benefit patients suffering from various skin and soft tissue disorders. FLE harnesses the power of fluorescence to trigger natural living biological systems. Current clinical programs have shown a high degree of efficacy and safety. Klox has developed, and is further developing, several easy to use, pathology-specific FLE to address conditions in the area of Wound Care, Dermatology, Animal Health and Oral Health. FLE has been designed to provide patients with a safe and comfortable experience with little to no downtime.



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  2. Scarcella, G, Gerber, PA, Edge, D, Nielsen, MCE. Effective removal of solar lentigines by combination of pre– And post–fluorescent light energy treatment with picosecond laser treatment. Clin Case Rep. 2020; 00 1– 4. httpsdoi.org10..pd

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  8. Koceva I, Rümmelein B, Gerber PA, Edge D, Nielsen MCE. Fluorescent light energy A new therapeutic approach to effectively treating acne conglobata and hidradenitis suppurativa. Clin Case Reports. 2019;7(9)1769-1772. doi10.1002ccr3.2.pdf

  9. Jalili A. Chromophore gel-assisted phototherapyChromophor-Gel-assistierte Phototherapie. J für Ästhetische Chir. 2019;12(S1)1-5. doi10.1007s12631-018-0121-z.pd

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  11. Liu RC, Makhija M, Wong XL, Sebaratnam DF. Treatment of granulomatous rosacea with chromophore gel-assisted phototherapy. Photodermatol Photoimmunol Photomed. March 2019phpp.12463. doi10.1111phpp.12463.pd

  12. Mahendran A, Wong XL, Kao S, Sebaratnam DF. Treatment of erlotinib-induced acneiform eruption with chromophore gel-assisted phototherapy. Photodermatology Photoimmunology and Photomedicine. 2019..pd

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  15. Sannino M, Lodi G, Dethlefsen MW, Nisticò SP, Cannarozzo G, Nielsen MCE. Fluorescent light energy Treating rosacea subtypes 1, 2, and 3. Clin Case Reports. 2018;6(12)2385-2390. doi10.1002ccr3.1891.pdf

  16. Davinelli S, Nielsen ME, Scapagnini G. Astaxanthin in skin health, repair, and disease A comprehensive review. Nutrients. 2018;10(4)522. doi10.3390nu10040522.pdf

  17. Fogacci T, Cattin F, Semprini G, Frisoni G, Fabiocchi L, Samorani D. The use of chromophore gel-assisted blue light phototherapy (Lumiheal) for the treatment of surgical site infections in breast surgery. Breast J. 2018;24(6)1135. d.pd

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  23. Nikolis A, Bernstein S, Kinney B, Scuderi N, Rastogi S, Sampalis JS. A randomized, placebo-controlled, single-blinded, split-faced clinical trial evaluating the efficacy and safety of KLOX-001 gel formulation with KLOX light-emittin.pdf

  24. Nikolis A, Fauverghe S, Vezina D, Scapagnini G. non-healing diabetic foot ulcer  A case report. 2016;4(2)25-31. httpwww.diabeticfootcanadajournal.cajournal-contentviewevaluation-of-biophotonic-therapy-in-a-non-healing-diabetic-foot-.pdf

  25.  Nikolis A, Grimard D, Pesant Y, Scapagnini G, Vezina D. A prospective case series evaluating the safety and efficacy of the Klox BioPhotonic System in venous leg ulcers. Chronic Wound Care Manag Res. 2016; Volume 3101-111. doi10.214.pdf